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Cot inhibitor-2 - CAS# 915363-56-3 rofen Calcium hydrate InChiKey: IWEQQRMGNVVKQW-OQKDUQJOSA-N

SKU: 51881399745

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Description

InChiKey: IWEQQRMGNVVKQW-OQKDUQJOSA-N

Chemical Name: GPR120-IN-1

Ca/c2*1-15(14-28-22(27)16-8-4-2-5-9-16)20(24)23-13-18(12-19(23)21(25)26)29-17-10-6-3-7-11-17

23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21

is a signal transducer and activator of transcription 3 (STAT3) inhibitor against human head and neck squamous cell carcinoma (HNSCC)

Cot inhibitor-2 - CAS# 915363-56-3 rofen Calcium hydrate InChiKey: IWEQQRMGNVVKQW-OQKDUQJOSA-NCot inhibitor 2 is a potent, selective and orally active cot (Tpl2 MAP3K8) inhibitor with an IC50 of 1. 6 nM. Cot inhibitor 2 inhibts TNF production in LPS stimulated human whole blood with an IC50 of 0. 3 M. Product information CAS Number: 915363 56 3 Molecular Weight: 539. 43 Formula: C26H25Cl2FN8 Synonym: 3 Quinolinecarbonitrile, 8 chloro 4 [(3 chloro 4 fluorophenyl)amino] 6 [[[1 (1 ethyl 4 piperidinyl) 1H 1,2,3 triazol 4 yl]methyl]amino] Chemical

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